Staff Engineer Agentic AI, Oncology Data Science & AI

AstraZeneca is a global, science-driven biopharmaceutical company. We are dedicated to discovering, developing, and delivering innovative, meaningful medicines and healthcare solutions that enrich the lives of patients. In AstraZeneca Oncology, our goal is to be at the forefront of developing the next generation of cancer therapies.

This Staff Engineer Agentic AI role is located in either Boston, MA, or Gaithersburg, MD

Main Duties And Responsibilities

There is an exciting opportunity for a talented and motivated Engineer to join the group as a Staff Engineer for Agentic AI. In this role, you will:

• Build Agentic AI driven solutions that tackle scientific research problems.
• Develop, test, and support Agentic tools for Genomics, Computational Pathology, Clinical Trials, etc.
• Automate complex data analysis processes.
• Introduce leading AI technologies applied to cancer research.
  
  

Essential Requirements

• Relevant graduate degree: Computer Science, Engineering, or Bioinformatics.
• Minimum of 10 years of applied experience in software engineering, data science, machine learning, bioinformatics, or relevant field.
• Hands-on experience building Agentic AI systems and deploying them to production.
• Programming skills: Solid Python and/or TypeScript programming skills
• Vast Experience in: Unix, SQL databases, REST APIs, Cloud computing (AWS).
• Vast Experience in software development best practices.
  
  

Desirable

• AI frameworks, such as Pydantic-AI, LangChain, etc.
• Experience in RAG, vector databases.
• An understanding of LLMs / Foundation models technologies.
• Experience in at least one compiled programming language (e.g. any of C, Java, Go, Rust, etc.).
  
  

The annual base pay for this position ranges from $177,520.00 - $266,280.00. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

10-Nov-2025

Closing Date

11-Dec-2025

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.